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右正中神经电刺激联合高压氧对颅脑外伤促醒作用及认知功能与脑血流的影响

作者 / Author:闫 峰 杨荣刚 沈江宜

右正中神经电刺激联合高压氧对颅脑外伤促醒作用及认知功能与脑血流的影响
闫 峰 杨荣刚 沈江宜
南阳南石医院,河南 南阳 473000
通信作者:闫峰
【摘要】 目的 探索右正中神经电刺激联合高压氧对颅脑外伤促醒作用及认知功能与脑血流的影响。方法 前瞻性纳入南阳南石医院 2021-01—2021-07 收治的 122 例颅脑外伤患者,根据随机数字表法分为 2 组,对照组 61 例采用右正中神经电刺激治疗,观察组 61 例采用右正中神经电刺激联合高压氧治疗,均治疗 6 个疗程后,比较 2 组治疗效果。结果 观察组治疗后 6 个疗程的
rCBV(3.56±0.67)mL/100 g、rCBF(43.57±5.22)mL/100 g、Vm(55.42±5.42)cm/s、Vp(68.42±4.51)m/s 以及脑干血流灌注(8.88±1.44)mL/(min·100 g)、丘脑血流灌注(12.56±1.82)mL/(min·100 g)、皮层区域血流灌注(13.58±2.37)mL/(min·100 g)改善情况优于对照组P
<0.05),治疗后 1 个疗程、3 个疗程、6 个疗程的疾病改善率分别为 50.82%、73.77%、95.08%均高于对照组P<0.05)。同时观察组治疗后 3 个疗程和 6 个疗程的 GCS 评分、MMSE 评分也高于对照组P<0.05)。结论 对颅脑外伤患者实施右正中神经电刺激联合高压氧治疗,能够提高脑血流量,改善认知功能。
【关键词】 颅脑外伤;正中神经电刺激;高压氧;促醒;认知功能;脑血流
【中图分类号】 R651.1+ 5 【文献标识码】 A 【文章编号】 1673-5110 (2022) 08-0946-07

 
Effect of right median nerve electrical stimulation combined with hyperbaric oxygen on the awakening,cognitive function and cerebral blood flow of craniocerebral injury
YAN Feng,YANG Ronggang,SHEN Jiangyi
Nanyang Nanshi Hospital,Nanyang 473000,China
Corresponding author:YAN Feng
AbstractObjective To explore the effect of electrical stimulation of right median nerve combined with hyperbaric oxygen on awakening effects of traumatic brain injury,cognitive function and cerebral blood flow.Methods Prospectively enrolled 122 cases of craniocerebral trauma patients were admitted between January 2021 and July 2021. They were divided into two groups according to the random number table method. Sixty-one cases of the control group were treated with electrical stimulation of the right median nerve,and the observation group sixty-one patients were treated with right median nerve electrical stimulation combined with hyperbaric oxygen therapy. After 6 courses of treatment,the therapeutic effects of the two groups were compared. Results The observation group’s rCBV(3.56±0.67)mL/100 g,rCBF(43.57±5.22)mL/100 g,Vm(55.42±5.42)cm/s,Vp(68.42±4.51)m/s and 6 courses after treatment in the observation group brainstem blood perfusion(8.88±1.44)mL/(min·100 g),thalamic blood perfusion(12.56±1.82)mL/(min·100 g),cortical area blood perfusion(13.58±2.37)mL/(min·100 g)im⁃ proved better than In the control group(P<0.05),the disease improvement rates of 1 course,3 courses,and 6 courses after treatment were 50.82%,73.77%,and 95.08%,which were higher than those of the control group(P<0.05). At the same time,the GCS scores and MMSE scores of the observation group were higher than those of the control group for 3 courses and 6 courses after treatment(P<0.05). Conclusion Applying right median nerve electrical stimulation combined with hyperbaric oxygen therapy to patients with craniocerebral trauma can increase cerebral blood flow and improve cognitive function.
Key words】 Craniocerebral trauma;Median nerve electrical stimulation;Hyperbaric oxygen;Awakening;Cognitive function;Cerebral blood flow

 

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