Mediating effect of resilience on the relationship between disability acceptance and quality of life in ischemic stroke patients ZHANG Ying，ZHOU Weiping，YANG Ying，WANG Zhumin，CHEN Ming Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine，Shanghai 200092，China Corresponding author: WANG Zhumin 【Abstract】 Objective To investigate the mediating effect of resilience on the relationship between disability acceptance and quality of life in patients with ischemic stroke. Methods Totally 415 patients with ischemic stroke admitted to Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine from March 2018 to January 2022 were selected. The clinical data，resilience，disability acceptance and quality of life of the patients were collected by general information questionnaire，Connor- Davidson resilience scale（CD-RISC），acceptancef disability scale（ADS）and stroke specific quality of life scale（SSQOL）. Multiple linear regression analyzed the mediating effect of resilience on disability acceptance and quality of life in patients with ischemic stroke. Results A total of 415 questionnaires were sent out，and 402 were effectively received with effective recovery rate of 96.87%. The total CD-RISC score（60.51±7.09）points was positively correlated with the total ADS score（87.13± 9.98）points and the total SSQOL score（149.28±56.95）points（P<0.05），and the total ADS score was positively correlated with the total SSQOL score（P<0.05）. Multiple linear regression analysis showed that ADS total score had a positive prediction effect on SSQOL total score（β=0.507，P<0.05）. After adding CD-RISC total score，ADStotal score had less effect on SSQOL total score（β 0.507 to 0.486）. These results suggest that resilience has a partial mediating effect on disability acceptance and quality of life in patients with ischemic stroke. Conclusion Resilience partially mediates the influence of disability acceptance on quality of life in patients with ischemic stroke.Enhancing resilience and improving disability acceptance can improve the quality of life of patients. 【Key words】 Ischemic stroke；Resilience；Disability acceptance；Quality of life；Mediation effect
